Identification of C. elegans serotonin receptor homologues in Globodera spp.

Globodera pallida and G. rostochiensis homologues of the five C. elegans genes encoding serotonin receptors were identified by reciprocal best BLAST hit analysis of the G. pallida [4] and G. rostochiensis [3] predicted gene complements.* All are G-protein coupled receptors with the exception of MOD-1 which is a serotonin-gated chloride channel. The likely gpa-ser-1 orthologue is incomplete in the genome assembly and encompassed by two adjacent gene models; this was confirmed by analysis of a transcriptome assembly produced using existing J2 RNAseq data [4]. # The complete sequence for gpa-ser-5 was not present in the genome assembly, but was identified from the transcriptome assembly.