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Structure of a Hsp90 Inhibitor bound to the N-terminus of Yeast Hsp90.

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Protein Data Bank Japan2023-12-13 更新2026-03-21 收录
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Structure of a Hsp90 Inhibitor bound to the N-terminus of Yeast Hsp90. Descriptor: 4-[4-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-METHYL-1H-PYRAZOL-5-YL]-6-ETHYLBENZENE-1,3-DIOL, ATP-DEPENDENT MOLECULAR CHAPERONE HSP82 Authors: Roe, S.M, Pearl, L.H, Prodromou, C. Deposit date: 2005-05-04 Release date: 2005-09-29 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors. Bioorg. Med. Chem. Lett., 15, 2005
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2005-05-04
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