Structure of cIAP1, BTK and BCCov
收藏Protein Data Bank Japan2024-10-16 更新2026-04-19 收录
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Structure of cIAP1, BTK and BCCov Descriptor: (4S)-4-[2-(2-{4-[(2E)-4-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}-4-oxobut-2-en-1-yl]piperazin-1-yl}ethoxy)acetamido]-1-{(2S)-2-cyclohexyl-2-[(N-methyl-L-alanyl)amino]acetyl}-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-L-prolinamide bound form, Baculoviral IAP repeat-containing protein 2, Tyrosine-protein kinase BTK, ... Authors: Schiemer, J.S, Calabrese, M.F. Deposit date: 2022-07-22 Release date: 2023-03-08 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.334 Å) Cite: A covalent BTK ternary complex compatible with targeted protein degradation. Nat Commun, 14, 2023
创建时间：
2022-07-22
