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A Public Benchmark for TCR-pMHC Prediction

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DataCite Commons2025-10-30 更新2026-02-09 收录
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https://figshare.com/articles/dataset/A_Public_Benchmark_for_TCR-pMHC_Prediction/30491582/1
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Accurate prediction of T cell receptor (TCR) specificity for cognate peptides presented by the major histocompatibility complex (pMHC) is a key challenge in understanding adaptive immunity and enabling immune-based therapeutics and diagnostics. Successful models predicting TCR-pMHC specificity must be able to generalize to novel TCRs and novel pMHCs not observed during model training. Here, we provide a labeled dataset intended for general use as a test of TCR-pMHC model generalization to novel TCRs specific for novel pMHCs.<br><br><b>Dataset file:</b> "immrep2025_for_release.tsv"<b>Detailed dataset description file</b>: "immrep25_dataset_and_methods.pdf"<br>
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figshare
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2025-10-30
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