Model for SINE RNA enhancement of viral gene expression.
收藏Figshare2016-02-23 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_Model_for_SINE_RNA_enhancement_of_viral_gene_expression_/1608361
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SINE RNAs are robustly induced in response to MHV68 infection. Through both MAVS-dependent and independent mechanisms, they stimulate the activity of the IKKβ component of the NF-κB pathway. IKKβ is co-opted by the virus to promote phosphorylation of RelA/p65, blunting the NF-κB transcriptional response. Additionally, IKKβ phosphorylates RTA, thereby enhancing viral gene expression and replication.
创建时间：
2016-02-23
