CREB1 binds IL-10 promoter
收藏reactome.org2025-01-21 收录
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The IL-10 promoter contains several transcription factor-responsive elements. (Asadullah et al 2003). In macrophages, the major source of IL-10, several receptor-mediated cytokine transcription end up in the activation of IL10 transcription factors, such as CREB (Platzer et al. 1995, Kelly et al 2010 & Sanin et al 2015)
IL-10启动子包含多个转录因子响应元件。(Asadullah 等人,2003)。在巨噬细胞中,IL-10的主要来源,多种受体介导的细胞因子转录最终导致IL10转录因子的激活,例如CREB(Platzer 等人,1995,Kelly 等人,2010 及 Sanin 等人,2015)
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