Crystal structure of SARS-CoV-2 Main Protease in complex with covalently bound GC376
收藏Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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Crystal structure of SARS-CoV-2 Main Protease in complex with covalently bound GC376 Descriptor: 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide Authors: Reinke, P.Y.A, Falke, S, Lieske, J, Ewert, W, Loboda, J, Rahmani Mashhour, A, Hauser, M, Karnicar, K, Usenik, A, Lindic, N, Lach, M, Boehler, H, Beck, T, Cox, R, Chapman, H.N, Hinrichs, W, Turk, D, Guenther, S, Meents, A. Deposit date: 2021-12-17 Release date: 2022-12-28 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Calpeptin is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections. Commun Biol, 6, 2023
创建时间:
2021-12-17



