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Crystal structure of A2A adenosine receptor A2AR-bRIL in complex with Compound50

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Protein Data Bank Japan2026-05-27 更新2026-05-30 收录
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Crystal structure of A2A adenosine receptor A2AR-bRIL in complex with Compound50 Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (4%{S})-2-[(3%{R},6%{S})-1-(1-ethyl-1%{H}-pyrazol-4-yl)-6-methylpiperidin-3-yl]-7-methoxy[1,2,4]triazolo[1,5-%{c}]quinazolin-5-amine, ... Authors: Krishnamurthy, H. Deposit date: 2026-01-25 Release date: 2026-05-20 Last modified: 2026-05-27 Method: X-RAY DIFFRACTION (2.59 Å) Cite: Discovery of MK-1088 as a Potent A 2A /A 2B Adenosine Receptor Dual-Antagonist for Cancer Immunotherapy. J.Med.Chem., 69, 2026

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2026-01-25
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