Expression profile and bioinformatics analysis of circular RNA in patients with senile osteoporotic vertebral compression fracture

To systematically characterize the circular RNA (circRNA) expression profiles in patients with senile osteoporotic vertebral compression fracture (OVCF) and predict the potential functions of the regulatory networks correlated with these differentially expressed circRNAs.We used RNA sequencing, Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), Reactome analysis and co-expression network analysis to profile the expression and regulation patterns of these circRNAs..