Data for: Advanced fibrosis of non-alcoholic steatohepatitis affects the significance of lipoprotein(a) as a cardiovascular risk factor

Lipoprotein(a) [Lp(a)] is an important independent cardiovascular risk factor. However, Lp(a) levels are lower in patients with chronic liver disease than in healthy subjects. Furthermore, Lp(a) levels decrease as residual liver function declines. Although non-alcoholic fatty liver disease (NAFLD), especially advanced non-alcoholic steatohepatitis (NASH), increases the risk of cardiovascular diseases, the relationship between serum Lp(a) level and NASH is unknown. Thus, we examined the relationship between serum Lp(a) levels and NAFLD and clarified the significance of Lp(a) measurements for cardiovascular disease screening in patients with NAFLD.

脂蛋白(a) [Lp(a)] 是一项重要的独立心血管风险因素。然而，与健康受试者相比，慢性肝病患者中的 Lp(a) 水平较低。此外，随着残余肝功能的下降，Lp(a) 水平亦呈现降低趋势。尽管非酒精性脂肪性肝病 (NAFLD)，尤其是进展期非酒精性脂肪性肝炎 (NASH) 会增加心血管疾病的风险，但血清 Lp(a) 水平与 NASH 之间的关系尚不明确。因此，我们探讨了血清 Lp(a) 水平与 NAFLD 之间的关系，并阐明了 Lp(a) 测量在 NAFLD 患者心血管疾病筛查中的重要性。