Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to glutamate and channel blocker spermidine (desensitized state)
收藏Protein Data Bank Japan2024-10-16 更新2026-06-30 收录
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Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to glutamate and channel blocker spermidine (desensitized state) Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GLUTAMIC ACID, Glutamate receptor 2, ... Authors: Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I. Deposit date: 2023-05-08 Release date: 2023-09-06 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (3.66 Å) Cite: Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2. Nat.Struct.Mol.Biol., 30, 2023
创建时间:
2023-05-08



