Expression data from mouse brain mononuclear cells
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE118805
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资源简介:
A membrane protein SIRPα (CD172a) interacts with another membrane protein CD47 and thereby constitutes a cell–cell contact signal. To investigate the functional role of CD47-SIRPα signal in the brain, we analyzed the effect of genetic ablation of CD47-SIRPα signal on the gene expression profile in specific brain cells by the use of microarrays. Total RNAs were prepared from the brain mononuclear cells of wild-type or CD47 knockout mice. Brain mononuclear cells were isolated by the use of Percoll gradient method. Total RNAs from seven (wild-type) and six (CD47 knockout) different animals were pooled and subjected to the analysis on Affymetrix Gene Chip.
创建时间:
2019-07-10



