Cis-Selective and Highly Enantioselective Hydrogenation of 2,3,4-Trisubstituted Quinolines
收藏Figshare2016-02-13 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Cis_Selective_and_Highly_Enantioselective_Hydrogenation_of_2_3_4_Trisubstituted_Quinolines/2161300
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A highly enantioselective cis-hydrogenation of 2,3,4-trisubstituted quinolines has been realized for the first time using chiral borane catalysts generated in situ from chiral dienes. A variety of tetrahydroquinoline derivatives containing three contiguous stereogenic centers were obtained in 76–99% yields with 82–99% ee’s.
创建时间：
2016-02-13
