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Crystal structure of the human CLR:RAMP1 extracellular domain heterodimer in complex with adrenomedullin 2/intermedin

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Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6d1u
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Crystal structure of the human CLR:RAMP1 extracellular domain heterodimer in complex with adrenomedullin 2/intermedin Descriptor: ADM2, Maltose-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, SODIUM ION, ... Authors: Pioszak, A, Roehrkasse, A. Deposit date: 2018-04-12 Release date: 2018-09-05 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structure-function analyses reveal a triple beta-turn receptor-bound conformation of adrenomedullin 2/intermedin and enable peptide antagonist design. J. Biol. Chem., 293, 2018
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2018-04-12
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