Characterization of R-loop-interacting proteins in embryonic stem cells reveals roles in ribosomal RNA processing and gene expression
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https://www.ncbi.nlm.nih.gov/sra/SRP293487
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资源简介：
We performed mRNA-seq on mouse embryonic stem cells, with four DEAD-box family proteins, DDX10, DDX24, DDX27, DDX54 being partially depleted using RNA interference. Knockdown of EGFP was carried out as a control. By comparing all four knockdowns, we observed misregulation of a highly-overlapping set of genes, indicating that they regulate mRNA levels through a shared pathway. Overall design: mRNA profiles of knockdowns of 4 Ddx genes, with EGFP knockdown as control, all performed with three biological replicates
创建时间：
2021-11-25
