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Crystal structure of human glutaminase in complex with L-glutamate

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Protein Data Bank Japan2023-08-30 更新2026-03-21 收录
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Crystal structure of human glutaminase in complex with L-glutamate Descriptor: GLUTAMIC ACID, GLYCEROL, Glutaminase kidney isoform, ... Authors: Karlberg, T, Welin, M, Andersson, J, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wikstrom, M, Schuler, H, Structural Genomics Consortium (SGC) Deposit date: 2008-04-29 Release date: 2008-07-01 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism. Proc.Natl.Acad.Sci.USA, 109, 2012
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2008-04-29
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