Landscape of Intratumoral NK Cell and ILC in Head and Neck Squamous Cell Carcinoma

In this study, total innate lymphoid cells (ILCs), including natural killer (NK) cells, were FACS-sorted from eight dissociated primary head and neck squamous cell carcinoma (HNSCC) tumors. In addition, ILCs and NK cells were sorted from peripheral blood of tumor patients. The ILCs and NK cells were analyzed by single-cell RNA sequencing (scRNA-seq) using the Smart-seq2 approach.]]>
Inclusion criteria include patients with biopsy proven HNSCC and no history of autoimmune disease. Exclusion criteria include patients less than 18 years of age.]]>