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Organotypic stromal cells impact endothelial cell transcriptome in 3D microvessel networks

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE206256
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ECFC-ECs are considered to be a plastic and naive endothelial cell. We combined ECFC-ECs with different stromal cells to see the resultant change of endothelial cell transcriptome due to different stromal cells. ECFC-ECs and a variety of organotypic stromal cells (Bone marrow, heart, skin, lung, pancreatic cancer, normal pancreas) were combined in 3D in vitro fibrin hydrogels and allowed to grow for 7 days into microvessel networks.
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2022-09-22
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