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Crystal structure of bace1 with novel inhibitor

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Protein Data Bank Japan2021-09-15 更新2026-03-21 收录
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Crystal structure of bace1 with novel inhibitor Descriptor: Beta-secretase 1, DI(HYDROXYETHYL)ETHER, Inhibitor (2R,5S,8S,12S,13S,16S,19S,22S)-16-(3-amino-3-oxopropyl)-2,13-dibenzyl-12,22-dihydroxy-8-isobutyl-19-isopropyl-3,5,17-trimethyl-4,7,10,15,18,21-hexaoxo-3,6,9,14,17,20-hexaazatricosan-1-oic acid, ... Authors: Chen, T.T, Chen, W.Y, Li, L, Xu, Y.C. Deposit date: 2012-06-05 Release date: 2013-01-16 Last modified: 2021-09-15 Method: X-RAY DIFFRACTION (1.59 Å) Cite: Cyanobacterial Peptides as a Prototype for the Design of Potent beta-Secretase Inhibitors and the Development of Selective Chemical Probes for Other Aspartic Proteases J.Med.Chem., 55, 2012
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2012-06-05
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