Crystal structure of FGFR4 kinase domain in complex with compound 5
收藏Protein Data Bank Japan2023-11-22 更新2026-03-21 收录
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Crystal structure of FGFR4 kinase domain in complex with compound 5 Descriptor: DIMETHYL SULFOXIDE, Fibroblast growth factor receptor 4, N-{4-[4-amino-3-(3,5-dimethyl-1-benzofuran-2-yl)-7-oxo-6,7-dihydro-2H-pyrazolo[3,4-d]pyridazin-2-yl]phenyl}prop-2-enamide Authors: Xu, Y, Liu, Q. Deposit date: 2018-11-29 Release date: 2019-11-06 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2 Å) Cite: Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design. J.Med.Chem., 62, 2019
创建时间:
2018-11-29



