Human norovirus GII.4 Houston protease in complex with rupintrivir

Human norovirus GII.4 Houston protease in complex with rupintrivir Descriptor: 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, Peptidase C37 Authors: Zhao, B, Pham, S.H, Neetu, N, Sankaran, B, Prasad, B.V.V. Deposit date: 2024-08-21 Release date: 2025-02-19 Last modified: 2025-03-12 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Conformational flexibility is a critical factor in designing broad-spectrum human norovirus protease inhibitors. J.Virol., 99, 2025