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The purinergic P2Y14 receptor links hepatocyte death to hepatic stellate cell activation and fibrogenesis in the liver

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Characterization of genes specifically expressed in mouse primary quiescent hepatic stellate cells (HSC) compared to the whole liver by RNA-sequencing and single cell RNA sequencing as well as effect of UDP-glucose treatment on mouse primary HSC. Bulk RNA sequencing of 13 samples: 4 quiescent HSC, 3 whole liver, 3 cultured-HSC untreated, 3 cultured HSC treated with UDP-glucose for 24h. Single cell RNA sequencing of normal untreated liver.

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