Wild-type Plasmodium falciparum DHFR-TS complexed with cycloguanil and NADPH
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Wild-type Plasmodium falciparum DHFR-TS complexed with cycloguanil and NADPH Descriptor: 1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine, Bifunctional dihydrofolate reductase-thymidylate synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Vanichtanankul, J, Chitnumsub, P, Kamchonwongpaisan, S, Yuthavong, Y. Deposit date: 2011-11-12 Release date: 2012-07-18 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Combined Spatial Limitation around Residues 16 and 108 of Plasmodium falciparum Dihydrofolate Reductase Explains Resistance to Cycloguanil. Antimicrob.Agents Chemother., 56, 2012
创建时间：
2011-11-12
