Profiling of human monoclonal antibodies targeting SARS-CoV-2 Omicron variant
收藏NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE203030
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资源简介：
We generated LNP-mRNA encoding B.1.1.529 SARS-CoV-2 spike, and intramuscularly administered it in a human IgG and IgK knock-in mouse. Single cell VDJ-seq unveiled the sequences of human monoclonal antibodies targeting the B.1.1.529 SARS-CoV-2 spike protein. Three sets of B cells were isolated and processed from the spleen, lymph nodes, bone marrows, or peripheral blood of the immunized mouse and then analyzed by scVDJ-seq.
创建时间：
2022-07-03
