Data from: Unravelling the history of hepatitis B virus genotypes A and D infection using a full-genome phylogenetic and phylogeographic approach

Hepatitis B virus (HBV) infection constitutes a global public health
problem. In order to establish how HBV was disseminated across different
geographic regions, we estimated the levels of regional clustering for
genotypes D and A. We used 916 HBV-D and 493 HBV-A full-length sequences
to reconstruct their global phylogeny. Phylogeographic analysis was
conducted by reconstruction of ancestral states using the criterion of
parsimony. The putative origin of genotype D was in North Africa/Middle
East. HBV-D sequences form low levels of regional clustering for the
Middle East and Southern Europe. In contrast, HBV-A sequences form two
major clusters, the first including sequences mostly from sub-Saharan
Africa, and the second including sequences mostly from Western and Central
Europe. Conclusion: We observed considerable differences in the global
dissemination patterns of HBV-D and HBV-A and different levels of
monophyletic clustering in relation to the regions of prevalence of each
genotype.