Mouse whole kidney, Dot1lAC vs. Dot1lf/f mice
收藏Alliance of Genome Resources2026-08-01 收录
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Transcriptional profiling of whole kidneys of adult Dot1lAC mice comparing control kidneys of their littermates Dot1lf/f mice fed a normal pellet Na+ diet. Goal was to determine the effects of inactivation of histone H3 K79 methyltransferase Dot1l in Aqp2-expressing cells in Dot1lAC on global kidney gene expression. Two-condition experiment, Dot1lAC vs. Dot1lf/f. Biological replicates: Total kidney RNAs from 4 mice/genotype were mixed within the same genotype.
