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Eukaryotic cells respond to DNA damage by arresting the cell cycle and modulating gene expression to ensure efficient DNA repair
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Bloom syndrome protein (BLM) is one of five human RecQ helicases which maintain genomic stability. Interaction of BLM with replication protein A (RPA) stimulates the DNA unwinding ability of BLM. The
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Cyclobutane pyrimidine dimers (CPD), as a common DNA damage caused by UV radiation, often lead to disastrous diseases. Here, we identified a photolyase from Arthrospira platensis (designated as Ap-phr
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Crystal structure of AfOgg1-K122S mutant bound to 8-OG DNA duplex in an intermediate state
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The histone chaperone CAF-1 prevents homologous recombination-mediated instability of the budding yeast ribosomal DNA during replication-coupled DNA double-strand break repair
Raw data for the paper, titled "The histone chaperone CAF-1 prevents homologous recombination-mediated instability of the budding yeast ribosomal DNA during replication-coupled DNA double-strand break
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In vitro DNA synthesis opposite oxazolone and repair of this DNA damage using modified oligonucleotides
Emphasis was placed in this work on the assessment of biological features of 2,2,4-triaminooxazolone, a major one-electron and (·)OH-mediated oxidation product of guanine. For this purpose, two oligon
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