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A novel CRISPR/Cas9 screening platform identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and anti-tumor immunity (CRISPR screen)

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE237969
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资源简介:
Investigation and validation of genes that regulate CXCL9 expression through a genome-wide in vitro CRISPR/Cas9 screen. AT-3 cells containing a GFP reporter for CXCL9 were transduced with a genome wide CRISPR library and stimulated with IFNg and TNF.
创建时间:
2023-07-24
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