Mitochondria-related gene sets are not enriched for associations with type 2 diabetes.

is the nominal gene set enrichment p-value for a given gene set gs, calculated here using the DIAGRAM+ T2D GWA study meta-analysis and an enrichment cutoff that equals the 95th percentile of all gene p-values, .
‡The effective number of genes is the number of genes analyzed after removing genes with no SNPs in their extended gene boundaries, and after correcting for chromosomal clustering of subsets of genes in a gene set, i.e. removing all but one gene of each subset of genes assigned the same best local SNP p-value (*).