BindingDB Entry 50016917: Discovery of A-770041, a src-family selective orally active lck inhibitor that prevents organ allograft rejection.

Small molecule binding data for protein Inhibitor of NF-kappa-B kinase (IKK), Interleukin-1 receptor-associated kinase 4, JAK2/TYK2, JAK3/JAK1, MAP kinase p38, MAP kinase-activated protein kinase 2, Mitogen-activated protein kinase kinase kinase 8, Protein kinase C (PKC), SRC, Tyrosine-protein kinase ITK/TSK, Tyrosine-protein kinase LCK, Tyrosine-protein kinase SYK, Tyrosine-protein kinase ZAP-70, VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor 2, Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), and cAMP-dependent protein kinase (PKA), Uniprot O14920, O15111, O15264, O94806, P05129, P05771, P06239, P06240, P06241, P07948, P08631, P09769, P12931, P17252, P17612, P22612, P22694, P24723, P29597, P35968, P41279, P41743, P43403, P43405, P49137, P52333, P53778, Q02156, Q02763, Q04759, Q05513, Q05655, Q08881, Q15139, Q15759, Q16539, and Q9NWZ3