Crystal structure of human Beta Secretase complexed with I21
收藏Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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Crystal structure of human Beta Secretase complexed with I21 Descriptor: 2-[(5R)-5-amino-5-methyl-4,16-dioxo-14-phenyl-3-oxa-15-azatricyclo[15.3.1.1~7,11~]docosa-1(21),7(22),8,10,12,14,17,19-octaen-19-yl]benzonitrile, Beta-secretase 1 Authors: Munshi, S. Deposit date: 2007-08-16 Release date: 2008-04-29 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitors. Bioorg.Med.Chem.Lett., 17, 2007
创建时间:
2007-08-16



