Microarray expression data derived from ovaries of women with Polycystic Ovary Syndrome and Female to Male Transexual individuals after treatment with Testosterone

This microarray analysis identified differentially regulated expression of 326 genes (p value=<0.05 and fold change of +/-2). Based on these genes, a biological LH network was generated consisting molecules where the significance of the association was measured by Fisher's exact test. We used microarray gene expression analysis to dissect the LH-induced gene expression in the ovaries of PCOS women. RNA was isolated from ovary biopsies of PCOS women and TSX individuals to investigate LH induced gene expression.