RNA sequencing data of periodonitis tissue

A total of 14 subjects participated in this study, including 7 patients with periodontitis and 7 healthy individuals. All subjects were enrolled from the Department of Oral and Maxillofacial Surgery, Nanjing Medical University Oral Hospital. Healthy controls were included for those who required gingival flap surgery to extract their impacted wisdom teeth. All subjects had no history of systemic diseases and inflammatory disorders such as hypertension, diabetes, cerebrovascular disease (CVD), inflammatory bowel disease (IBD). Besides, all subjects were not pregnant or breastfeeding and had no history of smoking. None of the subjects had taken drugs such as antibiotics or immunosuppressants in the previous 3 months. The gingival samples of the periodontitis group were collected from the areas of gingival recession.