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Notes on Exact Power Calculations for t Tests and Analysis of Covariance

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Figshare2019-12-20 更新2026-04-28 收录
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https://figshare.com/articles/dataset/_Exact_and_approximate_power_and_sample_size_calculations_for_analysis_of_covariance_in_randomized_clinical_trials_with_or_without_stratification_by_Yongqiang_Tang/11419368
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Tang derived the exact power formulas for t tests and analysis of covariance (ANCOVA) in superiority, noninferiority (NI), and equivalence trials. The power calculation in equivalence trials can be simplified by using Owen’s Q function, which is available in standard statistical software. We extend the exact power determination method for ANCOVA to unstratified and stratified multi-arm randomized trials. The method is applied to the design of multi-arm trials and gold standard NI trials. Supplementary materials for this article are available online.
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2019-12-20
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