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Crystal structure of SARS-CoV-2 main protease in complex with RS222C

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Protein Data Bank Japan2026-05-20 更新2026-05-24 收录
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Crystal structure of SARS-CoV-2 main protease in complex with RS222C Descriptor: 2-chloranyl-~{N}-[(~{R})-[1-(phenylmethyl)-1,2,3,4-tetrazol-5-yl]-pyridin-3-yl-methyl]-~{N}-(4-phenylphenyl)ethanamide, 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, ... Authors: Oerlemans, R, van der Straat, R, Marples, P, Koekemoer, L, Domling, A, Groves, M.R. Deposit date: 2025-03-06 Release date: 2026-03-18 Last modified: 2026-05-20 Method: X-RAY DIFFRACTION (2.044 Å) Cite: Ugi-Tetrazole-Derived alpha ‐Aminomethyl Scaffolds Reveal Unexpected Binding Modes in SARS-CoV‐2 3CLpro. Acs Med.Chem.Lett., 17, 2026

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2025-03-06
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