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RNA Sequencing Reveals Regulation of Marginal Zone B-Cell Differentiation by MicroRNA-146a

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE93252
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Splenocytes were FACS-sorted from Wild-type and Mir146a-/- mice to isolate specific B-cell developmental stages. Utilizing high-throughput sequencing, we comparatively analyzed developmental stage-specific splenic B cell transcriptomes, including Transitional-1 (T1), Transitional-2 (T2), Marginal zone (MZ) and Follicular (FO) in both Wild-type and Mir146a-/- B cells. Two replicates of each developmental stage were submitted for high-throughput sequencing. Transcriptomic profiles of primary B cell developmental subsets (T1, T2 MZ, FO) from Wild-type and Mir146a-/- mice in duplicate.
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2019-05-15
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