Association results of rs765250 with essential hypertension and blood pressure variation per cohort and meta-analyses.

aEffective number – maximum number of individuals available for analysis.
bOdds ratio and confidence intervals for EH using 10 K bootstrap samples. For the replication cohorts and meta analyses 90% confidence intervals are reported as all analyses were performed with the prior hypothesis that carriers of rs765250 allele A (A/A+A/G vs G/G) would be at increased risk for EH compared to G/G homozygotes.
cFor the replication cohorts and meta analyses one-tailed p-values are reported.
dFor EH and SBP results were combined under a fixed effects model. DBP showed evidence for heterogeneity and was analysed using a random-effects model.