p53 cancer mutant Y220C in complex with iodophenol-based small-molecule stabilizer JC769
收藏Protein Data Bank Japan2024-01-31 更新2026-04-19 收录
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p53 cancer mutant Y220C in complex with iodophenol-based small-molecule stabilizer JC769 Descriptor: 1,2-ETHANEDIOL, 4-[3,4-bis(fluoranyl)pyrrol-1-yl]-3,5-bis(iodanyl)-2-oxidanyl-benzoic acid, Cellular tumor antigen p53, ... Authors: Balourdas, D.I, Stephenson Clarke, J.R, Baud, M.G.J, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC) Deposit date: 2022-06-06 Release date: 2022-11-30 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.47 Å) Cite: Discovery of Nanomolar-Affinity Pharmacological Chaperones Stabilizing the Oncogenic p53 Mutant Y220C. Acs Pharmacol Transl Sci, 5, 2022
创建时间：
2022-06-06
