five

IRAK4 in complex with Compound 1

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Protein Data Bank Japan2024-10-09 更新2026-03-21 收录
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IRAK4 in complex with Compound 1 Descriptor: Interleukin-1 receptor-associated kinase 4, SULFATE ION, ~{N}1-(7,8-dihydro-6~{H}-cyclopenta[2,3]thieno[2,4-~{c}]pyrimidin-1-yl)-~{N}4,~{N}4-dimethyl-cyclohexane-1,4-diamine Authors: Ferguson, A.D. Deposit date: 2016-05-25 Release date: 2017-12-06 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.03 Å) Cite: Discovery and Optimization of Pyrrolopyrimidine Inhibitors of Interleukin-1 Receptor Associated Kinase 4 (IRAK4) for the Treatment of Mutant MYD88L265P Diffuse Large B-Cell Lymphoma. J. Med. Chem., 60, 2017
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2016-05-25
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