Crystal structure of SARS-CoV-2 Mpro-E166V mutant in complex with 13b-K
收藏Protein Data Bank Japan2025-09-03 更新2026-03-28 收录
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Crystal structure of SARS-CoV-2 Mpro-E166V mutant in complex with 13b-K Descriptor: Non-structural protein 11, ~{tert}-butyl ~{N}-[1-[(2~{S})-3-cyclopropyl-1-oxidanylidene-1-[[(2~{S},3~{S})-3-oxidanyl-4-oxidanylidene-1-[(3~{R})-2-oxidanylidenepyrrolidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-2-oxidanylidene-pyridin-3-yl]carbamate Authors: El Kilani, H, Hilgenfeld, R. Deposit date: 2023-01-24 Release date: 2024-08-07 Last modified: 2025-09-03 Method: X-RAY DIFFRACTION (2.2 Å) Cite: 13b-K and Nirmatrelvir Resistance Mutations of SARS-CoV-2 Main Protease: Structural, Biochemical, and Biophysical Characterization of Free Enzymes and Inhibitor Complexes Crystals, 15, 2025
创建时间：
2023-01-24
