Crystal structure of dipeptidyl peptidase IV in complex with a pyrimidinedione inhibitor 1
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Crystal structure of dipeptidyl peptidase IV in complex with a pyrimidinedione inhibitor 1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-(2-chlorobenzyl)-1,3-dimethyl-8-piperazin-1-yl-3,7-dihydro-1H-purine-2,6-dione, ... Authors: Zhang, Z, Wallace, M.B, Feng, J, Stafford, J.A, Kaldor, S.W, Shi, L, Skene, R.J, Aertgeerts, K, Lee, B, Jennings, A, Xu, R, Kassel, D, Webb, D.R, Gwaltney, S.L. Deposit date: 2009-01-27 Release date: 2010-02-16 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.69 Å) Cite: Design and Synthesis of Pyrimidinone and Pyrimidinedione Inhibitors of Dipeptidyl Peptidase IV. J.Med.Chem., 54, 2011
创建时间:
2009-01-27



