Additional file 2: of Inflammatory, regulatory, and autophagy co-expression modules and hub genes underlie the peripheral immune response to human intracerebral hemorrhage

Table S1. Subjects' demographic information and clinical characteristics. Table S2. List of all 21,175 genes and their respective modules. Table S3. Hypergeometric probability testing for all p(Dx) < 0.05 modules to all cell-types studied in this document. Table S4. List of the top 5% of the most interconnected genes (based on intramodular connectivity - kIN) within each module. Green-highlighted genes are amongst the top 1%. Table S5. IPA canonical pathways for only the hubs within modules with p(Dx) < 0.05. Pathways in peach color are significant following Benjamini-Hochberg (B-H) correction. Pathways in tan color - only following Fisher’s test. Table S6. p-values for each module with respect to diagnosis (A) and time since event (B). Table S7. IPA canonical pathways for all genes within modules that showed p(Dx) < 0.05. Pathways in peach color are significant following Benjamini-Hochberg correction. Pathways in tan color - only following Fisher’s test. Table S8. DAVID Gene Ontology results for all modules that showed p(Dx) < 0.05. Pathways in peach color are significant following Benjamini-Hochberg correction. Pathways in tan color - only following Fisher’s test. Table S9. List of differentially expressed genes (DEGs) and their respective fold-changes for genes amongst the 21,175 gene list (A). List of hub genes from the 1225 DEGs identified and their respective modules (B). IPA canonical pathways of only the list of 1225 DEGs (C). Cell-type involvement on all 1225 DEGs from this study (D). Cell-type involvement on only hub genes within the 1225 DEGs from this study (E). List of DEGs from this study that overlapped with the DEGs identified in Carmichael, et al. [15] (F). Cell-type enrichment on 46 DEGs that overlapped between this study and Carmichael’s study [15] (G). IPA canonical pathways of only the 46 DEGs that overlapped between this study and Carmichael’s study [15] (H). (XLSX 756 kb)