Crystal structure of E.coli dihydrofolate reductase in complex with NADPH and the inhibitor MS-SH08-17
收藏Protein Data Bank Japan2024-02-14 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/2ano
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of E.coli dihydrofolate reductase in complex with NADPH and the inhibitor MS-SH08-17 Descriptor: 1-{[N-(1-IMINO-GUANIDINO-METHYL)]SULFANYLMETHYL}-3-TRIFLUOROMETHYL-BENZENE, Dihydrofolate reductase, MANGANESE (II) ION, ... Authors: Summerfield, R.L, Daigle, D.M, Mayer, S, Jackson, S.G, Organ, M, Hughes, D.W, Brown, E.D, Junop, M.S. Deposit date: 2005-08-11 Release date: 2006-07-25 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.68 Å) Cite: A 2.13 A Structure of E. coli Dihydrofolate Reductase Bound to a Novel Competitive Inhibitor Reveals a New Binding Surface Involving the M20 Loop Region J.Med.Chem., 49, 2006
创建时间：
2005-08-11
