GLP Methyltransferase with Inhibitor EML741- P3121 Crystal Form
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GLP Methyltransferase with Inhibitor EML741- P3121 Crystal Form Descriptor: 1,2-ETHANEDIOL, 2-cyclohexyl-7-methoxy-N-[1-(propan-2-yl)piperidin-4-yl]-8-[3-(pyrrolidin-1-yl)propoxy]-3H-1,4-benzodiazepin-5-amine, Histone-lysine N-methyltransferase EHMT1, ... Authors: Horton, J.R, Cheng, X. Deposit date: 2018-08-30 Release date: 2019-02-27 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.947 Å) Cite: Discovery of a Novel Chemotype of Histone Lysine Methyltransferase EHMT1/2 (GLP/G9a) Inhibitors: Rational Design, Synthesis, Biological Evaluation, and Co-crystal Structure. J. Med. Chem., 62, 2019
创建时间：
2018-08-30
