STAT6 acetylation in renal cancer metastasis

NIAID Data Ecosystem2026-03-14 收录

肾癌转移机制

STAT6

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP357011 数据链接链接失效反馈

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资源简介：

To discover the natural inhibitor recognizing STAT6 acetylation at K284 and block advanced renal cancer.

创建时间：

2023-02-01

Effects of HIF2α in renal cancer metastasis and sensitivity to repurposed drugs

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药物重定位

Background: in clear cell renal cell carcinoma (ccRCC), 80% of cases have biallelic inactivation of VHL gene, leading to constitutive activation of both HIF1α and HIF2α. As HIF2α is the driver of the

NIAID Data Ecosystem70

Gene expression analysis of ccRCC cell line upon SETD2 rescue [RNAseq_JHRCC12]. Gene expression analysis of ccRCC cell line upon SETD2 rescue [RNAseq_JHRCC12]

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SETD2表观遗传调控

SETD2, a H3K36 trimethyltransferase, is frequently mutated in human cancers with the highest prevalence (13%) in clear cell renal cell carcinoma (ccRCC). Genomic profiling of primary ccRCC tumors reve

NIAID Data Ecosystem50

Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer

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表观遗传调控

Inactivation of the von Hippel-Lindau tumor suppressor gene, VHL, is an archetypical tumor-initiating event in clear cell renal carcinoma (ccRCC) that leads to the activation of hypoxia-inducible tran

NIAID Data Ecosystem30

The SWI/SNF chromatin remodeling factor DPF3 regulates metastasis of ccRCC by modulating TGF-β signaling.

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TGF-β信号通路

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

NIAID Data Ecosystem60

RNA-sequencing of neutrophils derived from OS-RC-2-bearing mice

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粒细胞转录组

Advanced clear cell renal cell carcinoma (ccRCC) frequently causes systemic inflammation. Here, we identified the functional role and regulatory mechanism of inflammation driven by advanced ccRCC cell

NIAID Data Ecosystem40

STAT6 acetylation in renal cancer metastasis

资源简介：

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