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RAC1 is an essential cofactor for estrogen receptor alpha [RNA-seq 2]

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NIAID Data Ecosystem2026-03-13 收录
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We identified a small GTPase protein RAC1 as an intrinsic cofactor in the estrogen receptor alpha (ER) complex that is required for the function of ER. MCF-7 cells were estrogen-deprived for 3 days before the cells were treated for 1 h during which the newly synthesized RNAs were labeled with BrU. The newly synthesized RNAs were purified and were subjected to RNA-seq.

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2021-10-27
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