Genome occupancy profiling by high throughput sequencing ChIP-seq of Brd4 with or without Doxycycline treatment to induce Med12 or Med23 shRNAs in MLL-AF9 transformed acute myeloid leukemia cells (RN2
Human iPS cells (WT ASE9203 cells) were obtained from Applied Stem Cell (ASC), and CRISPR-Cas9-mediated gene editing was completed by ASC using their proprietary CRISPR-Cas9 protocol to introduce the
Additional file 9: Table S8. KEGG enrichment analysis of the relapse hypo- and hyper- methylated genes separately, revealed common pathways among CLL cases.
The goals of this study are to identify ASXL2 binding sites in SKNO1 cells Examination of chromatin accessbility in AML1ETO9a leukemia with or without ASXL2
Central to the molecular pathogenesis of MLL leukaemia is the abnormal co-optation of members of transcription complexes including disrupter of telomeric silencing 1-like (DOT1L) and bromodomain conta