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Effect of endothelial ADAM10 deficiency on the aorta in an atherosclerosis mouse model. Effect of endothelial ADAM10 deficiency on the aorta in an atherosclerosis mouse model

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA861312
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Mice lacking ADAM10 in endothelial cells (Tie2Cre driven) and flox-control mice were injected with an AAV8-PCSK9 virus and put on a Western-type diet for 10 weeks to induce atherosclerosis. Aorta's (Thoracoabdominal) were isolated (removal of PVAT) and processed for RNA-sequencing. Overall design: RNAseq of mouse Aorta
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2022-07-22
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