Data for: Pros and cons of airlift and bubble column bioreactors: How internals improve performance

The DaRUS repository entails the simulation data for the publication "Pros and cons of airlift and bubble column bioreactors: How internals improve performance". Gas fermentation is a promising technology of high commercial interest, particularly for capturing CO2 and CO from industrial off-gases to reduce greenhouse gas emissions and to replace fossil fuels for bulk chemical production. Therefore, the ad initio evaluation of promising bioreactor settings is a crucial step. Whereas alternate configurations may be tested in laborious scale up studies, the tedious procedure may be accelerated by in silico studies that accompany or even partially replace wet-lab work. In this context, the current study compares various pneumatically agitated reactor types - bubble column reactor (BCR), annulus- and center-rising internal-loop airlift reactor (AR-IL-ALR and CR-IL-ALR), and external-loop airlift reactor (EL-ALR) - to identify advantages and disadvantages for the given application based on computational fluid dynamic (CFD) models. Process performance is optimized by the introduction of internal structures to guide the flow. Despite a 41 % increase in the mass transfer coefficient (k_L a) through internal modifications, the CR-IL-ALR still exhibited the poorest performance. The optimized AR-IL-ALR demonstrated good mixing and, after introducing an open-cone shaped internal in the head part and a conical bottom, superior mass transfer, achieving a 14 % enhancement in mass transfer coefficient to 315 1/h. This study thereby outlines the potential of internal structures for process improvement, as well as the value of a priori in silico design of reactor configurations.

DaRUS数据集包含了发表于《空运与泡状柱式生物反应器的利弊：内部结构如何提升性能》一文的模拟数据。气态发酵作为一种具有高度商业潜力的技术，尤其在捕获工业废气中的二氧化碳和一氧化碳以降低温室气体排放、替代化石燃料进行大宗化学品生产方面具有重要意义。因此，对具有潜力的生物反应器设置进行原位评估是至关重要的步骤。虽然可以通过耗时的规模扩大研究来测试替代配置，但通过伴随或部分替代湿实验工作的计算机模拟研究可以加速这一繁琐的过程。在此背景下，本研究对比了各种气力搅拌反应器类型——包括泡沫柱式反应器（BCR）、环形上升和中心上升内循环空升反应器（AR-IL-ALR和CR-IL-ALR）以及外循环空升反应器（EL-ALR）——基于计算流体动力学（CFD）模型，以识别针对特定应用的优势与不足。通过引入内部结构以引导流动，过程性能得到了优化。尽管通过内部修改，传质系数（k_L a）提高了41%，但CR-IL-ALR仍然表现出最差性能。经过优化的AR-IL-ALR展现了良好的混合效果，并在头部部分引入开放式圆锥形内部结构和锥形底部后，实现了优异的传质性能，传质系数提高了14%，达到315 1/h。因此，本研究概述了内部结构在过程改进方面的潜力，以及预先进行计算机模拟设计反应器配置的价值。