Table S2. Cell count and proportions in the 23 monocyte clusters

This study assesses the state of circulating monocytes in diabetes, with or without delayed gastric emptying, using a Streptozotocin (STZ)-induced mouse model, CyTOF, and computational analysis. Our findings show two classical monocyte subsets to be altered in the setting of diabetes with delayed gastric emptying and possible role of monocyte trafficking via the Ccr2-Ccl2 axis. All experiments were conducted in compliance with the National Institutes of Health Guide for the Care and Use of Laboratory Animals. All protocols were authorized by the Mayo Clinic Institutional Animal Care and Use Committee (A561020). Madhusudan Grover has received research grants from Takeda and Alfasigma Pharmaceuticals, as well as advisory fee from Evoke and Ardelyx Pharmaceuticals. Ruixue Hou, Yogesh Bhattarai, and Jill Wykosky are employees and shareholders of Takeda. Richard Myers and Alan J. Burns were employees during the time that this study was conducted and shareholders of Takeda. The rest of the authors declare no competing interests.